Tadadel 20 mg: Unraveling the Significance and Usage
Gui í a de Salud Masculina
- I. treatment of erectile dysfunction
- Second, the treatment of pulmonary hypertension
- Matters needing attention
tadalafil (tadalafil) 20mg is a drug dose used to treat erectile dysfunction (ED) and pulmonary hypertension (PAH) in men.
I. treatment of erectile dysfunction
1 、Mechanism of action
Tadalafil is a type 5 phosphodiesterase (PDE5) inhibitor. During sexual stimulation, nitric oxide (NO) is released from neuronal endings in the penile sponge. NO activates guanosine monophosphate cyclase and increases the level of cyclic guanosine monophosphate (cGMP), which leads to smooth muscle relaxation and blood flow into the corpus cavernosum. PDE5 breaks down cGMP, while tadalafil inhibits PDE5 and increases the concentration of cGMP. Maintain penile erectile function.
2 、Mode of use
Take it on demand: for patients with erectile dysfunction, take it as needed about 30 minutes-1 hour before sexual activity. however, tadalafil also has a long-term effect, and its effect can last about 36 hours, so it has more flexibility in medication time than some other short-acting ED drugs.
Take it regularly: some patients can also take it regularly once a day to get a more stable effect.
Second, the treatment of pulmonary hypertension
1 、Mechanism of action
In patients with pulmonary hypertension, tadalafil increases the content of cGMP in pulmonary vascular smooth muscle cells by inhibiting PDE5, so as to dilate pulmonary vessels, reduce pulmonary artery pressure, reduce right ventricular afterload, and improve patients' exercise ability and symptoms.
2 、Mode of use
-it is usually taken regularly once a day, and the specific dose adjustment and use need to be closely monitored by doctors, because many factors such as the severity of the patient's condition and other combined drugs need to be taken into account in the treatment of pulmonary hypertension.
Matters needing attention
1 、Adverse reaction
Common adverse reactions include headache, facial flushing, indigestion, nasal congestion, muscle pain, etc. Most of these adverse reactions are mild to moderate and usually relieve themselves after drug metabolism.
-in rare cases, serious adverse reactions may occur, such as sudden loss of vision or loss of vision (non-arterial anterior ischemic optic neuropathy, NAION). Although this is very rare, it requires immediate medical attention.
2 、Contraindication
-Tadalafil is prohibited in patients who are taking any form of nitrates (such as nitroglycerin, isosorbide dinitrate, etc.) because a combination of the two can lead to severe hypotension.
-you can't use it for people who are not allergic to Tadala.
The use of tadalafil 20mg must be carried out under the guidance of a doctor, and patients with any discomfort or abnormalities during use should seek medical advice in a timely manner.